Effect of spinal manipulation on brain functional activity in patients with lumbar disc herniation / 浙江大学学报·医学版

<p><b>OBJECTIVE</b>To investigate the effects of spinal manipulation (SM) on brain functional activity in patients with lumbar disc herniation (LDH).</p><p><b>METHODS</b>Eleven patients with LDH were recruited in the study. All patients received 6 times of lumbar SM treatment and then clinical efficacy was evaluated. All patients received brain functional magnetic resonance imaging (fMRI) scans before and after SM treatment.</p><p><b>RESULTS</b>Three subjects dropped out and 8 subjects completed the study, among whom 4 cases were effective and 4 ineffective after SM treatment. The required pressure value producing the same level (VAS 50) pain was (7.43 ± 1.47) kg and (10.53 ± 0.55) kg before and after SM treatment in effective patients(P<0.05); however, there was no significant difference in ineffective patients (P>0.05). Compared to pre-treatment level, the brain functional activity in effective patients was mainly inhibited, the inhibited areas were located in the right side of prefrontal cortex and cerebellum; while the brain functional activity was generally enhanced in ineffective patients.</p><p><b>CONCLUSION</b>SM can affect the brain functional activity of patients with LDH, the inhibited areas is mainly located in prefrontal cortex and cerebellum when SM treatment is effective.</p>

Construction of a human cervical spine with bilateral vertebral artery fluid-solid coupling model / 浙江大学学报·医学版

<p><b>OBJECTIVE</b>To construct a human cervical spine with bilateral vertebral artery fluid-solid coupling model.</p><p><b>METHODS</b>Helical CT images under the principle of reverse engineering and meshed in finite element model（FEM） related software were used to establish a human cervical spine with bilateral vertebral artery fluid-solid coupling model. In the process of modeling of vertebral body, vertebral artery, ligament, intervertebral disc, cartilage and endplate large anatomic data and cadaver experiments results were referenced. From the morphology and function the simulation of model with real physiological status was tested.</p><p><b>RESULTS</b>The study showed that the stress concentration on the surface of vertebral body and the blood wall of the bilateral vertebral artery, and the result of the volume flow rate-time curve of bilateral vertebral artery of the model were consistent with the published literatures. This model was well consistent with the clinical phenomenon.</p><p><b>CONCLUSION</b>The three-dimensional FEM of the human cervical spine established by the introduced method has been effectively verified. The modeling method would provide a new tool for research on the cervical spine biomechanics.</p>

Effects of electroacupuncture (EA) at early stage on functions of the limbs in the postoperative patient of hypertensive hemorrhage / 中国针灸

<p><b>OBJECTIVE</b>To investigate the rehabilitation effect of electroacupuncture (EA) at early stage on hemiplegia in the postoperative patient of hypertensive hemorrhage.</p><p><b>METHODS</b>Seventy-two cases of postoperative patient of hypertensive hemorrhage were divided into an EA group (n = 42) treated with EA at Quchi (LI 11), Shousanli (LI 10), Hegu (LI 4), Zusanli (ST 36), etc., from 1-3 days after operation, twice each day; and a control group (n = 30) with functional exercises. Their rehabilitation effects were compared after treatment of one month.</p><p><b>RESULTS</b>The rehabilitation effect in the EA group was significant better than that in the control group (P < 0.01).</p><p><b>CONCLUSION</b>EA at early stage has good recovery effect for the patient of hemiplegia after operation of hypertensive hemorrhage.</p>